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IDEAL timing of renal replacement therapy in critical care

Nature Reviews Nephrologyvolume 15pages56 (2019) | Download Citation

The IDEAL-ICU study reports no mortality benefit of early versus delayed initiation of renal replacement therapy (RRT) in patients with early septic shock and acute kidney injury. In the delayed initiation group, 17% of patients required emergency RRT but more than one-third spontaneously recovered renal function and did not require RRT.

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Author information


  1. Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University of Surrey, Guildford, UK

    • Lui G. Forni
  2. Intensive Care Unit, Royal Surrey County Hospital NHS Foundation Trust, Guildford, UK

    • Lui G. Forni
  3. Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria

    • Michael Joannidis


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Competing interests

L.G.F and M.J. have received lecture honoraria from Baxter and Fresenius.

Corresponding author

Correspondence to Lui G. Forni.

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