The IDEAL-ICU study reports no mortality benefit of early versus delayed initiation of renal replacement therapy (RRT) in patients with early septic shock and acute kidney injury. In the delayed initiation group, 17% of patients required emergency RRT but more than one-third spontaneously recovered renal function and did not require RRT.
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L.G.F and M.J. have received lecture honoraria from Baxter and Fresenius.
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Forni, L.G., Joannidis, M. IDEAL timing of renal replacement therapy in critical care. Nat Rev Nephrol 15, 5–6 (2019). https://doi.org/10.1038/s41581-018-0088-1
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DOI: https://doi.org/10.1038/s41581-018-0088-1
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