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The odyssey of risk stratification in acute kidney injury

Nature Reviews Nephrologyvolume 14pages660662 (2018) | Download Citation

A recent observational study reports that after cardiac surgery, clinical outcomes differ significantly between patients with the same stage of acute kidney injury (AKI) depending on the diagnosis criteria used: urine output, serum creatinine or both. This finding emphasizes the limitations of current criteria for AKI risk stratification and diagnosis.

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Author information


  1. Department of Internal Medicine II, Division of Nephrology, Pulmonology and Critical Care Medicine, University Hospital Giessen and Marburg, Giessen, Germany

    • Faeq Husain-Syed
  2. Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy

    • Claudio Ronco


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Competing interests

C.R. is a consultant for Ortho Clinical Diagnostics and Astute Medical, and has received honoraria for serving on the advisory board of Biomerieux. F. H.-S. declares no competing interests.

Corresponding author

Correspondence to Claudio Ronco.

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