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Preserving kidney health during intensive blood pressure control

Intensive lowering of blood pressure can decrease the risk of death and cardiovascular events in individuals with hypertension. However, a reanalysis of data from the SPRINT and ACCORD trials suggests that intensive blood pressure lowering increases the risk of chronic kidney disease.

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Fig. 1: Potential factors leading to renal damage when lowering blood pressure.


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The authors are supported by the US National Institutes of Health (grants DK116196 and DK096373 to M.L.S.S.-L. and DK116718 and DK096373 to R.A.G.).

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Correspondence to Maria Luisa S. Sequeira-Lopez or R. Ariel Gomez.

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The authors declare no competing interests.

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Sequeira-Lopez, M.L.S., Gomez, R.A. Preserving kidney health during intensive blood pressure control. Nat Rev Nephrol 14, 537–538 (2018).

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