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The origin, evolution and route to metastasis of clear cell RCC

Nature Reviews Nephrology (2018) | Download Citation

Three reports from the TRACERx Renal study delineate the precise origin and evolution of clear cell renal cell carcinoma in minute detail. The insights gained from these studies might provide improved disease prognostics and identify novel therapeutic targets.

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The authors’ work is supported by the Intramural Research Program of the US National Institutes of Health (NIH), National Cancer Institute, Center for Cancer Research.

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  1. Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA

    • Christopher J. Ricketts
    •  & W. Marston Linehan


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The authors declare no competing interests.

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Correspondence to W. Marston Linehan.

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