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Pitfalls in lipid mass spectrometry of mammalian samples — a brief guide for biologists

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Publications that report mass spectrometry analyses of lipids often include lipid species that probably do not exist in the samples. Here we provide recommendations for scientists on submitting lipid data, and for reviewers, editors and readers on evaluating these data, to reduce the reporting of erroneous lipid species.

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  • 10 July 2024

    In the version of the article initially published, refs. 10 and 11 were switched and have now been amended in the HTML and PDF version of the article.


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Correspondence to Tore Skotland or Kim Ekroos.

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K.E. is the owner of Lipidomics Consulting Ltd. The other authors declare no competing interests.

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Nature Reviews Molecular Cell Biology thanks the anonymous reviewer(s) for their contribution to the peer review of this work.

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Skotland, T., Ekroos, K., McDonald, J. et al. Pitfalls in lipid mass spectrometry of mammalian samples — a brief guide for biologists. Nat Rev Mol Cell Biol (2024).

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