Heterochromatin is a key characteristic of eukaryotic genomes. Since its cytological description nearly 100 years ago, our understanding of heterochromatin features and functions, including transcription repression and genome stability, have continuously evolved. In this Viewpoint article, experts provide their current opinions on heterochromatin definition, types and functional mechanisms.
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Bell, O., Burton, A., Dean, C. et al. Heterochromatin definition and function. Nat Rev Mol Cell Biol 24, 691–694 (2023). https://doi.org/10.1038/s41580-023-00599-7