This Genome Watch highlights different tools and strategies used to enhance the quality of metagenome-assembled genomes (MAGs) generated in microbiome studies.
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References
Bowers, R. M. et al. Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. Nat. Biotechnol. 35, 725–731 (2017).
Parks, D. H. et al. CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes. Genome Res. 25, 1043–1055 (2015).
Chklovski, A. et al. CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning. Nat. Methods 20, 1203–1212 (2023).
Mattock, J. & Watson, M. A comparison of single-coverage and multi-coverage metagenomic binning reveals extensive hidden contamination. Nat. Methods 20, 1170–1173 (2023).
Bornemann, T. L. V. et al. uBin: a manual refining tool for genomes from metagenomes. Environ. Microbiol. 25, 1077–1083 (2023).
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Malmstrom, R.R. Quality MAGnified. Nat Rev Microbiol 21, 771 (2023). https://doi.org/10.1038/s41579-023-00981-4
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DOI: https://doi.org/10.1038/s41579-023-00981-4
