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Science depends on nomenclature, but nomenclature is not science

The International Committee on Systematics of Prokaryotes (ICSP) has recently altered long-standing phylum names and given no guidance for taxonomy of uncultured or imperfectly cultured archaea and bacteria, disrupting progress towards a universal system of microbial taxonomy. Inclusion of new members into ICSP may help it to keep up to date.

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  1. Oren, A. & Garrity, G. M. Valid publication of the names of forty-two phyla of prokaryotes. Int. J. Syst. Evol. Microbiol. 71, 005056 (2021).

    Google Scholar 

  2. Lloyd, K. G., Steen, A. D., Ladau, J., Yin, J. & Crosby, L. Phylogenetically novel uncultured microbial cells dominate Earth microbiomes. mSystems 3, e00055-18 (2018).

    Article  CAS  Google Scholar 

  3. Rahi, P. Regulating access can restrict participation in reporting new species and taxa. Nat. Microbiol. 6, 1469–1470 (2021).

    Article  CAS  Google Scholar 

  4. Imachi, H. et al. Isolation of an archaeon at the prokaryote–eukaryote interface. Nature 577, 519–525 (2020).

    Article  CAS  Google Scholar 

  5. Meng, J. et al. Genetic and functional properties of uncultivated MCG archaea assessed by metagenome and gene expression analyses. ISME J. 8, 650–659 (2014).

    Article  CAS  Google Scholar 

  6. Parks, D. H. et al. A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life. Nat. Biotechnol. 36, 996–1004 (2018).

    Article  CAS  Google Scholar 

  7. Sanford, R. A., Lloyd, K. G., Konstantinidis, K. T. & Löffler, F. E. Microbial taxonomy run amok. Trends Microbiol. 29, 394–404 (2021).

    Article  CAS  Google Scholar 

  8. Murray, A. E. et al. Roadmap for naming uncultivated Archaea and Bacteria. Nat. Microbiol. 5, 987–994 (2020).

    Article  CAS  Google Scholar 

  9. Oren, A. et al. Proposal to include the rank of phylum in the International Code of Nomenclature of Prokaryotes. Int. J. Syst. Evol. Microbiol. 65, 4284–4287 (2015).

    Article  CAS  Google Scholar 

  10. Whitman, W. B. et al. Proposal of the suffix -ota to denote phyla. Addendum to ‘proposal to include the rank of phylum in the International Code of Nomenclature of Prokaryotes’. Int. J. Syst. Evol. Microbiol. 68, 967–969 (2018).

    Article  Google Scholar 

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Correspondence to Karen G. Lloyd.

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Lloyd, K.G., Tahon, G. Science depends on nomenclature, but nomenclature is not science. Nat Rev Microbiol 20, 123–124 (2022).

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