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Scientists on a RAMPAGE to find apicomplexan transcription start sites

This month’s Genome Watch highlights approaches that enable high-resolution mapping of transcription start sites in apicomplexan parasites.

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  1. Markus, B. M. et al. High-resolution mapping of transcription initiation in the asexual stages of Toxoplasma gondii. Front. Cell Infect. Microbiol. 10, 617998 (2020).

    Article  Google Scholar 

  2. Chappell, L. et al. Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq. BMC Genomics 21, 395 (2020).

    CAS  Article  Google Scholar 

  3. Batut, P. & Gingeras, T. R. RAMPAGE: promoter activity profiling by paired-end sequencing of 5′-complete cDNAs. Curr. Protoc. Mol. Biol. 104, 25B.11.21–25B.11.16 (2013).

    Article  Google Scholar 

  4. Adjalley, S. et al. Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum. Cell Rep. 14, 2463–2475 (2016).

    CAS  Article  Google Scholar 

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Correspondence to Johanna Hoshizaki or Marcus C. S. Lee.

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Hoshizaki, J., Lee, M.C.S. Scientists on a RAMPAGE to find apicomplexan transcription start sites. Nat Rev Microbiol 19, 483 (2021).

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