This month’s Genome Watch highlights approaches that enable high-resolution mapping of transcription start sites in apicomplexan parasites.
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References
Markus, B. M. et al. High-resolution mapping of transcription initiation in the asexual stages of Toxoplasma gondii. Front. Cell Infect. Microbiol. 10, 617998 (2020).
Chappell, L. et al. Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq. BMC Genomics 21, 395 (2020).
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Adjalley, S. et al. Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum. Cell Rep. 14, 2463–2475 (2016).
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Hoshizaki, J., Lee, M.C.S. Scientists on a RAMPAGE to find apicomplexan transcription start sites. Nat Rev Microbiol 19, 483 (2021). https://doi.org/10.1038/s41579-021-00587-8
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DOI: https://doi.org/10.1038/s41579-021-00587-8