Light sheets unveil host–microorganism interactions

This month’s Under the Lens discusses the application of light sheet fluorescence microscopy to observe the intestinal microbiota of live zebrafish, revealing unexpected host–microorganism interactions.

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References

  1. 1.

    Keller, P. J. et al. Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy. Science 322, 1065–1069 (2008).

  2. 2.

    Logan, S. L. et al. The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts. Proc. Natl Acad. Sci. USA 115, E3779–E3787 (2018).

  3. 3.

    Schlomann, B. H., Wiles, T. J. et al. Sublethal antibiotics collapse gut bacterial populations by enhancing aggregation and expulsion. Proc. Natl Acad. Sci. USA 116, 21392–21400 (2019).

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Correspondence to Sean C. Booth or William P. J. Smith.

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The authors declare no competing interests.

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Booth, S.C., Smith, W.P.J. Light sheets unveil host–microorganism interactions. Nat Rev Microbiol 18, 65 (2020). https://doi.org/10.1038/s41579-019-0318-y

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