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Genomics

Single cell–cell communication

Nature Reviews Genetics volume 24, page 488 (2023)Cite this article

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Cell–cell communication (CCC) is critical for the proper development and homeostasis of multicellular organisms. Communication pathways mediated by ligand–receptor pairs can be inferred from single-cell RNA sequencing (scRNA-seq) data, but existing approaches perform analyses at the level of cell types or clusters, thereby losing valuable cell-specific information. Now, an article in Nature Biotechnology describes single-cell-resolved interaction analysis through binning (Scriabin), a framework for scalable CCC analysis of scRNA-seq data at the level of individual cells.

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  1. Nature Reviews Genetics http://www.nature.com/nrg/

    Dorothy Clyde

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  1. Dorothy Clyde
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Correspondence to Dorothy Clyde.

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Clyde, D. Single cell–cell communication. Nat Rev Genet 24, 488 (2023). https://doi.org/10.1038/s41576-023-00631-8

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  • DOI: https://doi.org/10.1038/s41576-023-00631-8

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