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GENOME EDITING

Base editing takes a shot at disease in non-human primates

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References

Original articles

  1. Musunuru, K. et al. In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates. Nature 593, 429–434 (2021)

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  2. Rothgangl, T. et al. In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00933-4 (2021)

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Related article

  1. Rees, H. A. & Liu, D. R. Base editing: precision chemistry on the genome and transcriptome of living cells. Nat. Rev. Genet. 19, 770–788 (2018)

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Correspondence to Linda Koch.

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Koch, L. Base editing takes a shot at disease in non-human primates. Nat Rev Genet 22, 479 (2021). https://doi.org/10.1038/s41576-021-00382-4

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