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The importance of genetic counselling in genome-wide sequencing

Nature Reviews Genetics (2018) | Download Citation

Genome-wide sequencing (GWS) is the most sensitive test available for detecting pathogenic genetic variants. In line with guidelines in North America and Europe, best clinical practice requires GWS to be implemented as a holistic clinical service that includes both pre-test and post-test genetic counselling.

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Author information


  1. Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada

    • Alison M. Elliott
    •  & Jan M. Friedman
  2. BC Women’s Hospital and Health Centre, Vancouver, British Columbia, Canada

    • Alison M. Elliott
    •  & Jan M. Friedman


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A.M.E. contributed to all aspects of the article. J.M.F. made substantial contributions to discussions of the content and reviewed and/or edited the manuscript before submission.

Competing interests

The authors declare no competing interests.

Corresponding authors

Correspondence to Alison M. Elliott or Jan M. Friedman.

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