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  • Clinical Outlook
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Advances in the management of acute pancreatitis

Recent randomized controlled trials in acute pancreatitis have provided evidence that challenges current approaches to management, including fluid resuscitation, antibiotic administration, management of infected necrosis and use of early endoscopic retrograde cholangiopancreatography. The evidence means that we need to reassess the current management guidelines.

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Correspondence to Enrique de-Madaria.

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Competing interests

J.L.B. is a site investigator for the multicentre trial of CM4620 to treat acute pancreatitis funded by Calcimedica. E.d.-M. declares no competing interests.

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de-Madaria, E., Buxbaum, J.L. Advances in the management of acute pancreatitis. Nat Rev Gastroenterol Hepatol 20, 691–692 (2023).

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