The risk of acute liver injury (ALI) after COVID-19 vaccination (either the mRNA vaccine BNT162b2 or inactivated vaccine CoronaVac) was assessed in a case series analysis in Hong Kong of >2.3 million recipients of a COVID-19 vaccine who were at risk. The incidence of ALI after COVID-19 vaccination was very low and not increased compared with the non-exposure period; the majority of post-vaccination ALI was mild and self-limiting. The authors concluded that the potential benefits of mass vaccination for COVID-19 outweigh the risks of ALI from vaccination and SARS-CoV-2 infection.
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Wong, C. K. H. et al. Risk of acute liver injury following the mRNA (BNT162b2) and inactivated (CoronaVac) COVID-19 vaccines. J. Hepatol. https://doi.org/10.1016/j.jhep.2022.06.032 (2022)
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Ray, K. No increased risk of acute liver injury after COVID-19 vaccination. Nat Rev Gastroenterol Hepatol 19, 556 (2022). https://doi.org/10.1038/s41575-022-00666-y
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DOI: https://doi.org/10.1038/s41575-022-00666-y
