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What are the clinical settings and outcomes of lean NAFLD?

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased rapidly and is associated with obesity in epidemiology and pathogenesis. A new study reports that hepatic and extrahepatic complications can develop in lean individuals with NAFLD, highlighting the importance of metabolic phenotypes in NAFLD assessment instead of BMI-based approaches.

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Correspondence to Jian-Gao Fan.

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Ren, TY., Fan, JG. What are the clinical settings and outcomes of lean NAFLD?. Nat Rev Gastroenterol Hepatol 18, 289–290 (2021).

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