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IBD risk prediction using multi-ethnic polygenic risk scores

Inflammatory bowel disease (IBD) has emerged as a global disease, yet identifying those at higher risk of developing IBD remains challenging. A new study highlights the use of a multi-ethnic polygenic risk score to determine risk of inflammatory bowel disease in a large primary care population.

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A.N.A. is supported by grants from the National Institutes of Health, Crohn’s and Colitis foundation, and the Chleck Family Foundation.

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Correspondence to Ashwin N. Ananthakrishnan.

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A.N.A. has served on the scientific advisory board of Kyn Therapeutics, Sun Pharma and Gilead.

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Ananthakrishnan, A.N. IBD risk prediction using multi-ethnic polygenic risk scores. Nat Rev Gastroenterol Hepatol 18, 217–218 (2021).

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