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Point-of-care intestinal ultrasonography in inflammatory bowel disease

Intestinal ultrasonography (IUS) is an emerging, noninvasive, highly accessible and low-cost cross-sectional imaging modality for inflammatory bowel disease. This Comment summarizes how IUS in a point-of-care setting enables close patient monitoring.

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Fig. 1: IUS follow-up of a patient with Crohn’s disease.

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Authors and Affiliations

Authors

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Correspondence to Krisztina B. Gecse.

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Conflicts of interest

F.A.E.d-.V. reports honoraria fees from AbbVie and Janssen. B.V. reports financial support for research from Pfizer, lecture fees from Abbvie, Ferring, Janssen, R Biopharm and Takeda Pharmaceuticals, and consultancy fees from Guidepont, Janssen and Sandoz. C.M. reports lecture fees and/or consultancy fees from Abbvie, Biogen, Celgene, Dr. Falk Pharma Ferring, Galapagos, Gilead, Janssen, MSD Sharp & Dome, Pfizer, Roche and Takeda Pharmaceuticals. K.B.G. has received consultancy fees and/or speaker’s honoraria from AbbVie, Boehringer Ingelheim, Celltrion, Ferring, Gilead, Immunic Therapeutics, Janssen, Pfizer, Samsung Bioepis, Sandoz, Takeda and Tillotts.

Additional information

Related links

International Bowel Ultrasound Group: https://www.ibus-group.org/index.php/en/

U.S. National Library of Medicine Clinical Trials.gov: https://clinicaltrials.gov/

Supplementary information

Supplementary figure 1

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Supplementary Video 1 | Supplementary Figure 1a at baseline. Intestinal ultrasonography video of the sigmoid colon of a patient with ulcerative colitis at baseline.

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Supplementary Video 2 | Supplementary Figure 1a at 6 weeks. Intestinal ultrasonography video of the sigmoid colon of a patient with ulcerative colitis at 6 weeks after starting infliximab in combination with thiopurine.

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Supplementary Video 3 | Supplementary Figure 1a at 20 weeks. Intestinal ultrasonography video of the sigmoid colon of a patient with ulcerative colitis at 20 weeks after starting infliximab in combination with thiopurine.

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Supplementary Video 4 | Supplementary Figure 1b at baseline. Intestinal ultrasonography video of the terminal ileum of a patient with Crohn’s disease at baseline.

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Supplementary Video 5 | Supplementary Figure 1b at 12 weeks. Intestinal ultrasonography video of the terminal ileum of a patient with Crohn’s disease at 12 weeks after starting adalimumab monotherapy.

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Supplementary Video 6 | Supplementary Figure 1b at 20 weeks. Intestinal ultrasonography video of the terminal ileum of a patient with Crohn’s disease at 20 weeks after starting adalimumab monotherapy.

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de Voogd, F.A.E., Verstockt, B., Maaser, C. et al. Point-of-care intestinal ultrasonography in inflammatory bowel disease. Nat Rev Gastroenterol Hepatol 18, 209–210 (2021). https://doi.org/10.1038/s41575-021-00418-4

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