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HIV and the liver

Work during the past two decades has highlighted how HIV contributes to hepatic inflammation and fibrosis, leading to changes in the timing of antiretroviral therapy initiation and to improved diagnosis and management of liver disease in patients with HIV. As this population ages, clinician vigilance with early detection of emerging liver disease will be critical.

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Acknowledgements

M.B.B. is supported by the NIH grant 5R01DK108364.

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Competing interests

The authors declare no competing interests.

Correspondence to Meena B. Bansal.

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Fig. 1: Promotion of hepatic inflammation and fibrosis by HIV in chronic liver disease.