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Adipose tissue

Adipose tissue boosts muscle regeneration by supplying mesenchymal stromal cells

Nature Reviews Endocrinology volume 19, pages 317–318 (2023)Cite this article

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Tissue-resident stem cells have a central role in tissue regeneration, but other accessory cells are also required for efficient regeneration. A new study by Sastourné-Arrey and colleagues reveals a delicate mechanism of skeletal muscle regeneration through an unexpected type of inter-organ communication, in which stromal cells derived from adipose tissue support muscle regeneration.

Refers to Sastourné-Arrey, Q. et al. Adipose tissue is a source of regenerative cells that augment the repair of skeletal muscle after injury. Nat. Commun. 14, 80 (2023).

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  1. Division of Cell Heterogeneity, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

    Akiyoshi Uezumi

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  1. Akiyoshi Uezumi
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Correspondence to Akiyoshi Uezumi.

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The author declares no competing interests.

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Uezumi, A. Adipose tissue boosts muscle regeneration by supplying mesenchymal stromal cells. Nat Rev Endocrinol 19, 317–318 (2023). https://doi.org/10.1038/s41574-023-00831-6

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  • DOI: https://doi.org/10.1038/s41574-023-00831-6

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