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Do diet and microbes really ‘PREDICT’ cardiometabolic risks?

It is commonly accepted that dietary habits and cardiometabolic disorders are connected to the composition of the gut microbiota. However, can we really generalize and predict health by screening faecal microorganisms? A study has taken the plunge and identified a vast range of correlations supporting this possibility.

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Fig. 1: Complex relationships between gut microorganisms, diet and host metabolism.


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P.D.C. is senior research associate at FRS-FNRS (Fonds de la Recherche Scientifique) and acknowledges the support of grants from FNRS (Projet de Recherche PDR-convention: FNRS T.0030.21-P, FRFS-WELBIO: WELBIO-CR-2019C-02R).

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Correspondence to Patrice D. Cani.

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Competing interests

P.D.C. is the inventor on patent applications dealing with the use of A. muciniphila and its components in the treatment of metabolic disorders. P.D.C. is co-founder of A-Mansia biotech SA.

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Cani, P.D., Van Hul, M. Do diet and microbes really ‘PREDICT’ cardiometabolic risks?. Nat Rev Endocrinol 17, 259–260 (2021).

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