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REPRODUCTIVE ENDOCRINOLGY

Towards subtypes — deep endometriosis oestrogen receptor-α expression

Nature Reviews Endocrinology volume 16, pages 541–542 (2020)Cite this article

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Most research treats endometriosis as a single entity, potentially obscuring informative subtype-specific associations with risk factors, biomarkers and treatment responses. A 2020 study raises the hypothesis that deep endometriosis oestrogen receptor-α expression might be associated with progestin treatment and the degree of post-surgical excision pain.

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Acknowledgements

The authors acknowledge the support of Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) grants R01 HD094842 and R21 HD096358.

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Authors and Affiliations

  1. Division of Adolescent and Young Adult Medicine, Department of Pediatrics, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA

    Amy L. Shafrir & Stacey A. Missmer

  2. Boston Center for Endometriosis, Brigham and Women’s Hospital and Boston Children’s Hospital, Boston, MA, USA

    Amy L. Shafrir & Stacey A. Missmer

  3. Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA

    Stacey A. Missmer

  4. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA

    Stacey A. Missmer

Authors
  1. Amy L. Shafrir
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  2. Stacey A. Missmer
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Correspondence to Amy L. Shafrir.

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Competing interests

S.M. serves as an advisory board member for AbbVie and served as a working group member for Roche. A.S. and S.M. receive funding support from the J. Willard and Alice S. Marriott and the Marriott Daughters’ Foundations – all unrelated to this work.

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Shafrir, A.L., Missmer, S.A. Towards subtypes — deep endometriosis oestrogen receptor-α expression. Nat Rev Endocrinol 16, 541–542 (2020). https://doi.org/10.1038/s41574-020-0394-0

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