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ISLET BIOLOGY

Transplantation of stem cell-derived pancreatic islet cells

Nature Reviews Endocrinology volume 17, pages 7–8 (2021)Cite this article

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A large fraction of patients with diabetes mellitus require insulin treatment to control glucose metabolism; however, this treatment brings risks of hypoglycaemia and provides suboptimal metabolic control. Transplantation of stem cell-derived pancreatic islet cells could be an ideal solution, which is approaching clinical translation.

Refers to Augsornworawat, P., Maxwell, K. G., Velazco-Cruz, L. & Millman, J. R. Single-cell transcriptome profiling reveals beta cell maturation in stem cell-derived islets after transplantation. Cell Rep. 32, 108067 (2020).

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Authors and Affiliations

  1. Diabetes Research Institute and Cell Transplant Center, University of Miami Miller School of Medicine, Miami, FL, USA

    Giacomo Lanzoni & Camillo Ricordi

  2. Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA

    Giacomo Lanzoni & Camillo Ricordi

  3. Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA

    Giacomo Lanzoni & Camillo Ricordi

Authors
  1. Giacomo Lanzoni
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  2. Camillo Ricordi
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Correspondence to Camillo Ricordi.

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Lanzoni, G., Ricordi, C. Transplantation of stem cell-derived pancreatic islet cells. Nat Rev Endocrinol 17, 7–8 (2021). https://doi.org/10.1038/s41574-020-00430-9

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  • DOI: https://doi.org/10.1038/s41574-020-00430-9

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