Who would have thought — myokines two decades on

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In 2012, we were invited by Nature Reviews Endocrinology to write a Review titled Muscles, exercise and obesity: skeletal muscle as a secretory organ’. At the time, following our findings in the 2000s, we knew the concept of skeletal muscle as an endocrine organ was important. Eight years on, the magnitude of the importance of this concept surprises us.

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Correspondence to Mark A. Febbraio.

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Febbraio, M.A., Pedersen, B.K. Who would have thought — myokines two decades on. Nat Rev Endocrinol 16, 619–620 (2020). https://doi.org/10.1038/s41574-020-00408-7

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