Exercise is a potent modulator of intestinal microbiota composition and function. In 2019, several studies uncovered biologically important links between skeletal muscle and the gut microbiota, revealing how the gut bacteria respond to an exercise challenge and have reciprocal roles in fuel availability, muscle function and endurance performance.
Treadmill endurance running capacity is decreased and ex vivo skeletal muscle contractile function is impaired in mice with a depleted gut microbiota: restoring the gut microbiota reverses these impairments4,5.
Faecal microbiota transplantation of Veillonella atypica from humans after a strenuous exercise challenge significantly increases submaximal run time to exhaustion in mice9.
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The author declares no competing interests.
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Hawley, J.A. Microbiota and muscle highway — two way traffic. Nat Rev Endocrinol 16, 71–72 (2020). https://doi.org/10.1038/s41574-019-0291-6
Frontiers in Nutrition (2020)
Journal of the International Society of Sports Nutrition (2020)