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DIABETES

Prevention begets prevention — lessons from the Da Qing Study

Lifestyle interventions in patients with prediabetes can delay the onset of type 2 diabetes mellitus, but long-term data on diabetes complications are lacking. A new report from the Da Qing Study provides data on the effect of lifestyle interventions on diabetes mellitus complications and mortality in patients with prediabetes who were followed up for 30 years.

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References

  1. Uusitupa, M. et al. Ten-year mortality and cardiovascular morbidity in the Finnish Diabetes Prevention study—secondary analysis of the randomized trial. PLOS ONE 4, e5656 (2009).

    Article  Google Scholar 

  2. Diabetes Prevention Program Research Group. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes study. Lancet Diabetes Endocrinol. 3, 866–875 (2015).

    Article  Google Scholar 

  3. Gong, Q. et al. Long-term effects of a randomised trial of a 6-year lifestyle intervention in impaired glucose tolerance on diabetes-related microvascular complications: the China Da Qing Diabetes Prevention Outcome Study. Diabetologia 54, 300–307 (2011).

    Article  CAS  Google Scholar 

  4. Li, G. et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention study: a 20-year follow-up Study. Lancet 371, 1783–1789 (2008).

    Article  Google Scholar 

  5. Li, G. et al. Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: a 23-year follow-up study. Lancet Diabetes Endocrinol. 2, 474–480 (2014).

    Article  Google Scholar 

  6. Gong, Q. et al. Morbidity and mortality after lifestyle intervention for people with impaired glucose tolerance: 30-year results of the Da Qing Diabetes Prevention Outcome Study. Lancet Diabetes Endocrinol. 7, 452–461 (2019).

    Article  Google Scholar 

  7. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 317, 703–713 (1998).

    Article  Google Scholar 

  8. McAuley, P. A. et al. Fitness, fatness, and survival in adults with prediabetes. Diabetes Care 37, 529–536 (2014).

    Article  CAS  Google Scholar 

  9. Johnson, J. L. et al. Ten-year legacy effects of three eight-month exercise training programs on cardiometabolic health parameters. Front. Physiol. 10, 452 (2019).

    Article  Google Scholar 

  10. Echouffo-Tcheugui, J. B. & Dagogo-Jack, S. Preventing diabetes mellitus in developing countries. Nat. Rev. Endocrinol. 8, 557–562 (2012).

    Article  Google Scholar 

Download references

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Correspondence to Samuel Dagogo-Jack.

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Competing interests

S.D.J. is a principal investigator in the multicentre Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study.

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Dagogo-Jack, S. Prevention begets prevention — lessons from the Da Qing Study. Nat Rev Endocrinol 15, 442–443 (2019). https://doi.org/10.1038/s41574-019-0227-1

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