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Low-calorie diets in the management of type 2 diabetes mellitus

Type 2 diabetes mellitus is common, disabling and expensive, despite improved glucose-lowering management and guidelines. Its dominant cause is weight gain, with ectopic fat accumulation in vital organs, reflected by a large waist circumference. Addressing the underlying cause, by low-calorie formula diets and integrated support for long-term weight-loss maintenance, produces remissions in almost half the treated population.

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Correspondence to Michael E. J. Lean.

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M.E.J.L. has consulted for Counterweight Ltd, with fees paid to the University of Glasgow.

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Lean, M.E.J. Low-calorie diets in the management of type 2 diabetes mellitus. Nat Rev Endocrinol 15, 251–252 (2019). https://doi.org/10.1038/s41574-019-0186-6

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