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Dad’s diet – smRNA methylation signatures in sperm pass on disease risk

Nature Reviews Endocrinologyvolume 14pages446447 (2018) | Download Citation

Metabolic disease risk is thought to arise at the interface of genetics and the environment. A new study identifies an enzyme that modifies small non-coding RNA and is required for passing on the effects of high-fat diet from father to offspring.

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Author information


  1. Department of Zoology, University of Cambridge, Cambridge, UK

    • Rahia Mashoodh
  2. Department of Genetics, University of Cambridge, Cambridge, UK

    • Anne C. Ferguson-Smith


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Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Anne C. Ferguson-Smith.

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