Correction to: Nature Reviews Drug Discovery (2022) https://doi.org/10.1038/s41573-022-00472-w, published online 30 May 2022

The chemical structures in Table 2 were out of place by one row and have now been correctly placed. Also, the molecular weight of SEP-856 in Figure 2 is 183 Da, not 138 Da, and this has been corrected.