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Therapeutic targeting of the complement system
The complement pathway plays key roles in host defence, but its excessive activation or dysregulation can lead to a variety of disorders. This poster overviews strategies to therapeutically intervene in the pathway and the new generation of complement inhibitors that are now in the clinic.
This poster is freely available online thanks to support from Alexion Pharmaceuticals Inc., Roche and Novartis Pharma AG. As always, Springer Nature retains sole responsibility for all editorial content.
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Ricklin, D., Mastellos, D.C. & Lambris, J.D. Therapeutic targeting of the complement system. Nat Rev Drug Discov (2019). https://doi.org/10.1038/s41573-019-0055-y
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DOI: https://doi.org/10.1038/s41573-019-0055-y