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Financial toxicity: a common problem affecting patient care and health

Financial toxicity describes the negative effects of the economic burden of medical care on patients that potentially lead to poor well-being and quality of life. Co-ordinated efforts at the care provider, health system, insurance and government level, supported by emerging research into remedial approaches, are needed to address this problem.

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Fig. 1: Contributors, aspects, modifiers and potential effects of financial toxicity of medical care.

References

  1. Yabroff, K. R., Zhao, J., Han, X. & Zheng, Z. Prevalence and correlates of medical financial hardship in the USA. J. Gen. Intern. Med. 34, 1494–1502 (2019).

    Article  Google Scholar 

  2. Valero-Elizondo, J. et al. Atherosclerotic cardiovascular disease, cancer, and financial toxicity among adults in the United States. JACC CardioOncol. 3, 236–246 (2021).

    Article  Google Scholar 

  3. Lyman, G. H. & Kuderer, N. Financial toxicity, financial abuse, or financial torture: let’s call it what it is! Cancer Invest. 38, 139–142 (2020).

    Article  CAS  Google Scholar 

  4. Fitch, M. I., Sharp, L., Hanly, P. & Longo, C. J. Experiencing financial toxicity associated with cancer in publicly funded healthcare systems: a systematic review of qualitative studies. J. Cancer Surviv. https://doi.org/10.1007/s11764-021-01025-7 (2021).

    Article  PubMed  Google Scholar 

  5. Gordon, L. G., Merollini, K. M. D., Lowe, A. & Chan, R. J. A systematic review of financial toxicity among cancer survivors: we can’t pay the co-pay. Patient 10, 295–309 (2017).

    Article  Google Scholar 

  6. Ramsey, S. D. et al. Financial insolvency as a risk factor for early mortality among patients with cancer. J. Clin. Oncol. 34, 980–986 (2016).

    Article  CAS  Google Scholar 

  7. Bradley, C. J., Yabroff, K. R. & Shih, Y. T. A coordinated policy approach to address medical financial toxicity. JAMA Oncol. 7, 1761–1762 (2021).

    Article  Google Scholar 

  8. Patel, M. R. et al. A scoping review of behavioral interventions addressing medical financial hardship. Popul. Health Manag. 24, 710–721 (2021).

    Article  Google Scholar 

  9. Pisu, M. et al. Perspectives on conversations about costs of cancer care of breast cancer survivors and cancer center staff: a qualitative study. Ann. Intern. Med. 170 (Suppl. 9), 54–61 (2019).

    Article  Google Scholar 

  10. Jones, S. M., Henrikson, N. B., Panattoni, L., Syrjala, K. L. & Shankaran, V. A theoretical model of financial burden after cancer diagnosis. Future Oncol. 16, 3095–3105 (2020).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors are thankful for funding for the Emotional Well-being and Economic Burden Research Network from the National Center For Complementary and Integrative Health (NCCIH) and the Office Of The Director of the National Institutes Of Health (OD) (U24AT011310).

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Correspondence to Maria Pisu.

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Pisu, M., Martin, M.Y. Financial toxicity: a common problem affecting patient care and health. Nat Rev Dis Primers 8, 7 (2022). https://doi.org/10.1038/s41572-022-00341-1

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