Nature Reviews Disease Primers 4, Article number: 27 (2018) https://doi.org/10.1038/s41572-018-0025-4 Published online 01 October 2018

In the originally published version of Figure 3, APP was incorrectly linked to CMA. In addition, the label for NCP2 was omitted, and GlcSph was incorrectly labelled as GlcCer. This figure has now been corrected.