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Ensuring completeness and timeliness of cancer treatment guidelines

Timely and comprehensive updating of treatment guidelines remains a challenge and necessity in medical oncology. Herein we discuss our assessment of how trial results with four off-patent drugs have been considered for integration into major guidelines in the absence of a commercial sponsor, in which we found reasons for concern.

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The authors thank P. Pantziarka (Anticancer Fund) for discussions and assistance in preparing this article.

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Correspondence to Gauthier Bouche.

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The authors declare no competing interests.

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ASCO Guidelines Evidence Submission Form:

ASCO Guidelines Methodology Manual:

ESMO eUpdate standard operating procedures:

NCCN Submission Request History:

Transparency of the NCCN Guidelines Development Process:

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Bouche, G., Meheus, L. Ensuring completeness and timeliness of cancer treatment guidelines. Nat Rev Clin Oncol 19, 563–564 (2022).

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