To achieve health equity, we advocate for the overrepresentation of particular racial and ethnic minority groups so that analyses of group-specific treatment effects can be optimally powered. A paradigm shift is needed across multiple stakeholders, as well as in the engagement of community programmes, the role of investigators from racial and ethnic minority backgrounds and clinical trial regulations.
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References
Owens-Walton, J., Williams, C., Rompré-Brodeur, A., Pinto, P. A. & Ball, M. W. Minority enrollment in phase ii and iii clinical trials in urologic oncology. J. Clin. Oncol. https://doi.org/10.1200/JCO.21.01885 (2022).
National Cancer Institute. Surveillance, Epidemiology, End Results Program. Number of Persons by Race and Hispanic Ethnicity for SEER Participants (2020 Census Data), https://seer.cancer.gov/registries/data.html (accessed 17 March 2022).
Borno, H. T. et al. How current reporting practices may mask differences: a call for examining cancer-specific demographic enrollment patterns in cancer treatment clinical trials. Contemp. Clin. Trials Commun. 16, 100476 (2019).
Anderson, A. & Griffith, D. M. Measuring the Trustworthiness of Health Care Organizations and Systems. Milbank Q. https://doi.org/10.1111/1468-0009.12564 (2022).
Jones, L. & Wells, K. Strategies for academic and clinician engagement in community-participatory partnered research. J. Am. Med. Assoc. 297, 407–410 (2007).
NMF. NMF Diversity in Clinical Trials Research Program, https://nmfonline.org/scholarships-programs/diversity-in-research/clinical-trials-research/ (accessed 17 March 2022).
Borno, H. T. et al. Implementation of a multisite financial reimbursement program in cancer clinical trials integrated with patient navigation: a pilot randomized clinical trial. JCO Oncol. Pract. https://doi.org/10.1200/OP.21.00328 (2022).
Strauss, D. H., White, S. A. & Bierer, B. E. Justice, diversity, and research ethics review. Science 371, 1209–1211 (2021).
McCaskill-Stevens, W., McKinney, M. M., Whitman, C. G. & Minasian, L. M. Increasing minority participation in cancer clinical trials: the minority-based community clinical oncology program experience. J. Clin. Oncol. 23, 5247–5254 (2005).
Borno, H. T. et al. Integration of electronic pathology reporting with clinical trial matching for advanced prostate cancer. Urol Oncol. 39, 494.e7–494.e14 (2021).
Acknowledgements
Funding was provided in part by the Memorial Sloan Kettering Cancer Center Support Grant (P30 CA008748-50).
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The North American Association of Central Cancer Registries: https://www.naaccr.org/
The NCI Community Oncology Research Program: https://ncorp.cancer.gov/
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Gomez, S.L., Tsai, C.J. Is representation enough or should we be targeting equitable inclusion?. Nat Rev Clin Oncol 19, 429–430 (2022). https://doi.org/10.1038/s41571-022-00635-z
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DOI: https://doi.org/10.1038/s41571-022-00635-z