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BREAST CANCER

Interval breast cancers — insights into a complex phenotype

Nature Reviews Clinical Oncology volume 17, pages 138–139 (2020)Cite this article

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Interval invasive breast cancers diagnosed after a normal mammogram but before the next screening examination have a different tumour biology from that of screen-detected breast cancers, and thus are not detected on mammography. Understanding the genetics and biology of interval invasive cancers could inform better approaches to detection.

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Acknowledgements

The authors received funding support from the National Cancer Institute (P01CA154292, K24CA169004 and K08CA237829).

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Authors and Affiliations

  1. Division of General Internal Medicine, University of California, San Francisco, San Francisco, CA, USA

    Yiwey Shieh & Elad Ziv

  2. Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, CA, USA

    Karla Kerlikowske

  3. General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA

    Karla Kerlikowske

Authors
  1. Yiwey Shieh
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  2. Elad Ziv
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  3. Karla Kerlikowske
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Correspondence to Karla Kerlikowske.

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The authors declare no competing interests.

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Shieh, Y., Ziv, E. & Kerlikowske, K. Interval breast cancers — insights into a complex phenotype. Nat Rev Clin Oncol 17, 138–139 (2020). https://doi.org/10.1038/s41571-020-0327-9

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