Continuing to improve outcomes of men with metastatic prostate cancer

In the TITAN and ENZAMET trials, unprecedented overall survival outcomes were observed in patients with metastatic castration-sensitive prostate cancer receiving an agent targeting the androgen receptor in addition to androgen-deprivation therapy early in the course of their disease. Herein, I discuss both trials in the context of other studies in this disease setting.

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Correspondence to Fred Saad.

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Competing interests

F.S. is a paid consultant for and receives research funding from Astellas, Bayer, Janssen and Sanofi.

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