Helicobacter pylori eradication therapy is effective in preventing gastric cancer, even in patients with advanced pre-neoplastic lesions (gastric atrophy and/or intestinal metaplasia). We must now focus on how to accomplish the goal of eliminating gastric cancer-related death worldwide; strategies for screening and treatment of gastric neoplasia (primary prevention) and post-treatment surveillance (secondary prevention) are discussed herein.
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The author acknowledges support from the US NIH National Institute of Diabetes and Digestive and Kidney Diseases (grant DK62813); the Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (grant 16H05191); and from the Japan Society for the Promotion of Science (Core-to-Core Program).
The author declares no competing interests.
GLOBOCAN 2012: http://globocan.iarc.fr/
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Yamaoka, Y. How to eliminate gastric cancer-related death worldwide?. Nat Rev Clin Oncol 15, 407–408 (2018) doi:10.1038/s41571-018-0029-8
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