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Rearrangements come to Scholl

Recent findings on the skeletal rearrangement of polycyclic aromatics under oxidative and acidic conditions are envisioned to help development of these Scholl reactions into a more useful and versatile method for synthesizing polycyclic aromatics on the basis of rational design rather than luck.

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Fig. 1: Scholl reactions with and without rearrangement.


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Correspondence to Qian Miao.

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Miao, Q. Rearrangements come to Scholl. Nat Rev Chem (2021).

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