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NATURAL PRODUCT SYNTHESIS

Botanical bonanza

Nature Reviews Chemistry volume 5, page 222 (2021)Cite this article

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Isodon scoparius is a rare plant that has long been used in traditional Chinese medicine to reduce fever. Studies of the secondary metabolites from this species have already borne fruit with the identification of scopariusic acid as well as scopariusicides A and B, three terpenoid natural products that all have interesting immunosuppressive activities. Now, Pema-Tenzin Puno, Ang Li and their co-workers from the Kunming Institute of Botany, the Shanghai Institute of Materia Medica and the Shanghai Institute of Organic Chemistry have added a fourth natural product to that list — (−)-isoscopariusin A — reporting its structure and a gram-scale synthesis.

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  1. Nature Reviews Chemistry http://www.nature.com/natrevchem/

    Stephen G. Davey

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  1. Stephen G. Davey
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Correspondence to Stephen G. Davey.

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Davey, S.G. Botanical bonanza. Nat Rev Chem 5, 222 (2021). https://doi.org/10.1038/s41570-021-00271-8

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