Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Quantum mechanics: Tunnel visions of reactions


  1. 1

    Doubleday, C. et al. Heavy-atom tunneling calculations in thirteen organic reactions: tunneling contributions are substantial, and Bell's formula closely approximates multidimensional tunneling at ≥ 250 K. Angew. Chem. Int. Ed. (2017)

  2. 2

    Greer E. M. et al. Computational evidence for heavy-atom tunneling in the Bergman cyclization of a 10-membered-ring enediyne. J. Am. Chem. Soc. 135, 10194–10197 (2013)

    CAS  Article  Google Scholar 

Download references


Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Graziano, G. Quantum mechanics: Tunnel visions of reactions. Nat Rev Chem 1, 0086 (2017).

Download citation


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing