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Cardiac amyloidosis

Patisiran is beneficial for the treatment of TTR cardiac amyloidosis

Nature Reviews Cardiology (2023)Cite this article

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Treatment with the small interfering RNA patisiran preserves functional capacity and improves health status and quality of life in patients with transthyretin (TTR) cardiac amyloidosis, according to data from the 12-month double-blind period of the ongoing APOLLO-B trial.

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References

Original article

  • Maurer, M. S. et al. Patisiran treatment in patients with transthyretin cardiac amyloidosis. N. Engl. J. Med. 389, 1553–1565 (2023)

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Related article

  • Aimo, A. et al. RNA-targeting and gene editing therapies for transthyretin amyloidosis. Nat. Rev. Cardiol. 19, 655–667 (2022)

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Nature Reviews Cardiology http://www.nature.com/nrcardio/

    Irene Fernández-Ruiz

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  1. Irene Fernández-Ruiz
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Correspondence to Irene Fernández-Ruiz.

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Cite this article

Fernández-Ruiz, I. Patisiran is beneficial for the treatment of TTR cardiac amyloidosis. Nat Rev Cardiol (2023). https://doi.org/10.1038/s41569-023-00955-2

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  • DOI: https://doi.org/10.1038/s41569-023-00955-2

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