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CARDIAC HYPERTROPHY

Piezo1 senses pressure overload and initiates cardiac hypertrophy

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Original article

  • Yu, Z.-Y. et al. Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice. Nat. Cardiovasc. Res. 1, 577–591 (2022)

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Related article

  • Saucerman, J. J. et al. Mechanical regulation of gene expression in cardiac myocytes and fibroblasts. Nat. Rev. Cardiol. 16, 361–378 (2019)

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Correspondence to Gregory B. Lim.

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Lim, G.B. Piezo1 senses pressure overload and initiates cardiac hypertrophy. Nat Rev Cardiol 19, 503 (2022). https://doi.org/10.1038/s41569-022-00746-1

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  • DOI: https://doi.org/10.1038/s41569-022-00746-1

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