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Caffeine consumption and cardiovascular health

Nature Reviews Cardiology volume 19, pages 429–430 (2022)Cite this article

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Moderate coffee consumption (2–5 cups per day) has been consistently associated with a lower risk of cardiovascular disease in epidemiological studies. For most individuals, a caffeine intake of up to 400 mg per day is safe and moderate coffee consumption can be included as part of a healthy lifestyle.

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Fig. 1: Mendelian randomization using genetic variants that affect caffeine metabolism.

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Authors and Affiliations

  1. Departments of Exercise and Nutrition Sciences and Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA

    Rob M. van Dam

  2. Departments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA

    Rob M. van Dam & Frank B. Hu

  3. Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

    Frank B. Hu

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  1. Rob M. van Dam
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Correspondence to Rob M. van Dam or Frank B. Hu.

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van Dam, R.M., Hu, F.B. Caffeine consumption and cardiovascular health. Nat Rev Cardiol 19, 429–430 (2022). https://doi.org/10.1038/s41569-022-00719-4

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