Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

The importance of including diverse populations in cancer genomic and epigenomic studies

Nature Reviews Cancer volume 19, pages 361–362 (2019)Cite this article

Subjects

There is increasing emphasis on studying cancers in diverse populations both within and between countries. In this Comment article, I argue that genomic, epigenomic and other studies on cancer in diverse populations across low-income and middle-income countries are essential in order to reduce worldwide cancer burden and improve global health.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Arteaga, C. L. et al. AACR cancer progress report 2014. Clin. Cancer Res. 20, S1–S112 (2014).

    Article  Google Scholar 

  2. Chan-On, W. et al. Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. Nat. Genet. 45, 1474–1478 (2013).

    Article  CAS  Google Scholar 

  3. Vaz, M. et al. Chronic cigarette smoke-induced epigenomic changes precede sensitization of bronchial epithelial cells to single-step transformation by KRAS mutations. Cancer Cell 32, 360–376 (2017).

    Article  CAS  Google Scholar 

  4. Xia, L. et al. CHD4 has oncogenic functions in initiating and maintaining epigenetic suppression of multiple tumor suppressor genes. Cancer Cell 31, 653–668 (2017).

    Article  CAS  Google Scholar 

  5. Jusakul, A. et al. Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma. Cancer Discov. 7, 1116–1135 (2017).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Cancer Centre, Singapore, Singapore

    Bin Tean Teh

  2. SingHealth Duke-NUS Global Health Institute, Singapore, Singapore

    Bin Tean Teh

Authors
  1. Bin Tean Teh
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bin Tean Teh.

Ethics declarations

Competing interests

The author declares no competing interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Teh, B.T. The importance of including diverse populations in cancer genomic and epigenomic studies. Nat Rev Cancer 19, 361–362 (2019). https://doi.org/10.1038/s41568-019-0158-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41568-019-0158-0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer