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Topological control of synthetic morphogenesis

Organs in the human body have complex networks of fluid-filled tubes and loops with different geometries and topologies. By studying self-organized, synthetic tissues, the link between topological transitions and the emergence of tissue architecture was revealed.

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Fig. 1: Pharmacological control of organoid topology and shape.

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This is a summary of: Ishihara, K. et al. Topological morphogenesis of neuroepithelial organoids. Nat. Phys. https://doi.org/10.1038/s41567-022-01822-6 (2022).

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Topological control of synthetic morphogenesis. Nat. Phys. (2022). https://doi.org/10.1038/s41567-022-01843-1

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  • DOI: https://doi.org/10.1038/s41567-022-01843-1

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