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Protein biophysics

Hidden depths of protein folding

Nature Physics volume 19, pages 8–9 (2023)Cite this article

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Watching a single protein molecule fold for days reveals rare excursions into configurations that were previously hidden from observation by high energy barriers.

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Fig. 1: Probing remote regions of protein folding landscapes with long-duration force spectroscopy measurements.

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Author information

Authors and Affiliations

  1. Department of Physics, University of Alberta, Edmonton, Alberta, Canada

    Krishna Neupane & Michael T. Woodside

  2. Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada

    Michael T. Woodside

  3. Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada

    Michael T. Woodside

Authors
  1. Krishna Neupane
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  2. Michael T. Woodside
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Correspondence to Krishna Neupane or Michael T. Woodside.

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Neupane, K., Woodside, M.T. Hidden depths of protein folding. Nat. Phys. 19, 8–9 (2023). https://doi.org/10.1038/s41567-022-01828-0

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