The cost of synchronization

Synchronization of biochemical oscillators that are responsible for biological rhythms costs free energy. This theoretical result suggests that part of the adenosine triphosphate molecules consumed by a Kai oscillator is necessary for synchronization.

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Fig. 1: Illustration of the exchange reactions that modify the phase of two clocks.


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Correspondence to Andre C. Barato.

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Barato, A.C. The cost of synchronization. Nat. Phys. 16, 5 (2020).

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