The electrochemical triggering of fluorophores in dSTORM enables one to actively control their switching behaviours, resulting in improved spatial resolution and precise molecular counting down to the single molecule level in emitter-dense areas.
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References
Rust, M. J., Bates, M. & Zhuang, X. W. Nat. Methods 3, 793–795 (2006).
Heilemann, M., van de Linde, S., Mukherjee, A. & Sauer, M. Angew. Chem. Int. Ed. Engl. 48, 6903–6908 (2009).
Huang, B., Babcock, H. & Zhuang, X. Cell 143, 1047–1058 (2010).
Schermelleh, L. et al. Nat. Cell Biol. 21, 72–84 (2019).
Lelek, M. et al. Nat. Rev. Methods Primers 1, 39 (2021).
Betzig, E. et al. Science 313, 1642–1645 (2006).
Sharonov, A. & Hochstrasser, R. M. PNAS 103, 18911–18916 (2006).
Schnitzbauer, J., Strauss, M. T., Schlichthaerle, T., Schueder, F. & Jungmann, R. Nat. Protoc. 12, 1198–1228 (2017).
Nicovich, P. R., Owen, D. M. & Gaus, K. Nat. Protoc. 12, 453–460 (2017).
Marsh, R. J. et al. Nat. Methods 15, 689–692 (2018).
Yang, Y. et al. Nat. Photon. https://doi.org/10.1038/s41566-024-01431-0 (2024).
Balzarotti, F. et al. Science 355, 606–612 (2017).
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Franke, C., Eggeling, C. Electrochemistry meets Photophysics for single-molecule localization. Nat. Photon. 18, 643–645 (2024). https://doi.org/10.1038/s41566-024-01459-2
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DOI: https://doi.org/10.1038/s41566-024-01459-2