News & Views | Published:

IMAGING

Measuring molecular mass with light

Nature Photonicsvolume 12pages380381 (2018) | Download Citation

Interferometric analysis of the weak light scattered from proteins makes it possible to determine their mass.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    Young, G. et al. Science 360, 423–427 (2018).

  2. 2.

    Chaste, J. et al. Nat. Nanotech. 7, 300–303 (2012).

  3. 3.

    Hanay, M. S. et al. Nat. Nanotech. 7, 602–608 (2012).

  4. 4.

    Lindfors, K., Kalkbrenner, T., Stoller, P. & Sandoghdar, V. Phys. Rev. Lett. 93, 037401 (2004).

  5. 5.

    Kukura, P. et al. Nat. Methods 6, 923–927 (2009).

  6. 6.

    Curtis, A. S. G. J. Cell. Biol. 20, 199–215 (1964).

  7. 7.

    Cole, D., Young, G., Weigel, A., Sebesta, A. & Kukura, P. ACS Photon. 4, 211–216 (2017).

  8. 8.

    Liebel, M., Hugall, J. T. & van Hulst, N. F. Nano Lett. 17, 1277–1281 (2017).

  9. 9.

    Jain, A. et al. Nature 473, 484–488 (2011).

  10. 10.

    Taylor, M. A. et al. Nat. Photon. 7, 229–233 (2013).

Download references

Author information

Affiliations

  1. CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, FL, USA

    • Kyu Young Han
  2. Departments of Biophysics and Biophysical Chemistry, Biophysics, and Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA

    • Taekjip Ha
  3. Howard Hughes Medical Institute, Baltimore, MD, USA

    • Taekjip Ha

Authors

  1. Search for Kyu Young Han in:

  2. Search for Taekjip Ha in:

Corresponding authors

Correspondence to Kyu Young Han or Taekjip Ha.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/s41566-018-0202-8

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing