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DNA nanotechnology

DNA nanoswitches pack an anti-cancer punch

Nature Nanotechnology (2024)Cite this article

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A DNA origami nanodevice presents its hidden death ligand pattern in the acidic tumour microenvironment to kill cancerous cells, opening opportunities for effective and safe cancer therapy.

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Fig. 1: Schematics of the pH-regulated DNA-origami robotic switch.

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Authors and Affiliations

  1. Department of Cell Biology & Nanobiology Institute, Yale University, West Haven, CT, USA

    Kun Zhou & Chenxiang Lin

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  1. Kun Zhou
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  2. Chenxiang Lin
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Correspondence to Chenxiang Lin.

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The authors declare no competing interests.

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Zhou, K., Lin, C. DNA nanoswitches pack an anti-cancer punch. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01749-4

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